Too much Ibuprofen linked to male infertility

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Ibuprofen has been linked to fertility problems in men.

However, Kristensen emphasises that despite the results of the study, men should not stop taking the drug.

Bernard Jégou, co-author and director of the Institute of Research in Environmental and Occupational Health in France, and a team of French and Danish researchers, began by exploring the health effects of pregnant women taking any of the 3 most common OTC pain relievers: acetaminophen, aspirin, and ibuprofen.

The researchers found that, compared with the placebo group, the men who took ibuprofen experienced a 23 percent increase in levels of luteinizing hormone (LH) - a hormone that's secreted by the pituitary gland and stimulates the production of testosterone - after two weeks. Research released in February 2017 also found that it could increase the risk of heart attacks. "Using a unique combination of a randomized, controlled clinical trial and ex vivo and in vitro approaches, we report a univocal depression of important aspects of testicular function, including testosterone production, after use of over-the-counter ibuprofen", the paper reads. 17 men were given a daily dose of 1200mg if ibuprofen.

The condition, generally associated with elderly men and linked to reproductive and physical disorders, including infertility, results in the body having higher levels of luteinizing hormone (LH) than testosterone.

'Several studies have shown mild analgesics exposure during foetal life is associated with anti-androgenic effects and congenital malformations.

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If you are concerned about your levels of testosterone and your ibuprofen use, though, it's worth chatting to your GP so you can get checked out and find a way to deal with chronic aches and pains in a healthy way.

"However, this is now speculative". In both cases, ibuprofen had a direct effect on the testicles.

Men who dream of starting a family may want to pass on the ibuprofen the next time they have a headache.

As Forbes notes, this is the first study to provide evidence with regards to the negative impact of ibuprofen on testicular physiology.

For short-term ibuprofen use the effects of compensated hypogonadism are reversible, however the researchers state how it is unknown whether these effects are reversible for long-term ibuprofen use.

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