6 2017 fired a vice president who had previously been seen as a likely successor, removing an obstacle to the presidential ambitions of Mugabe's wife.
Mugabe's dramatic move came after a weekend of high drama between Mnangagwa and Grace Mugabe after which the president appeared to finally back his wife in the succession race.
The fact that Mnangagwa's removal was announced by a government minister and not the chief secretary to the president and cabinet highlighted the deterioration in their relationship.
Moyo said Mnangagwa had exhibited traits of disloyalty, disrespect and deceitfulness.
In 2014, Mugabe expelled his female deputy Joice Mujuru on allegations of plotting to topple his through, among others, witchcraft allegations.
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Simon Khaya Moyo said on Monday that President Robert Mugabe, 93, has fired the vice president who had always been viewed as his successor.
"It had become evident that his conduct in the discharge of his duties had become inconsistent with his official responsibilities", Moyo said.
On Sunday Grace Mugabe called Mnangagwa a "coup plotter" and a "coward" in a speech that ruffled more than a few feathers in Zanu-PF.
Mr Mugabe, 93, has been president of Zimbabwe since 1987 and was prime minister for seven years before that. "I can do a great job'".